Influence of renin-angiotensin-aldosterone system block on the systemic inflammation activity and left ventricle remodeling in patients with Q-myocardial infarction after thrombolysis

Authors

  • S. M. Kyselov

DOI:

https://doi.org/10.14739/2310-1210.2015.3.44420

Keywords:

Myocardial Infarction, Interleukin-6, Interleukin-1-beta

Abstract

Aim. Inflammatory cytokines play a role in adaptive postinfarction remodeling of the heart. In order to study the influence of treatment on the condition of systemic inflammatory markers, the incidence of post-infarction aneurysm and thrombus formation in the left ventricle of patients with Q-wave myocardial infarction after thrombolytic therapy serum levels of interleukin-6, interleukin-1-beta, von-Willebrand factor, fibrinogen were studied in 92 patients with immunoassay analysis.

Results and discussion. Remodeling, systolic and diastolic function of the heart were evaluated with echocardiography. Under the influence of the treatment reduction of systemic inflammatory markers activity was showed, which accompanied by improvement of left ventricular systolic function and low frequency of left ventricle aneurysm and thrombus formation.

References

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How to Cite

1.
Kyselov SM. Influence of renin-angiotensin-aldosterone system block on the systemic inflammation activity and left ventricle remodeling in patients with Q-myocardial infarction after thrombolysis. Zaporozhye Medical Journal [Internet]. 2015Jun.15 [cited 2024Jun.22];17(3). Available from: http://zmj.zsmu.edu.ua/article/view/44420

Issue

Section

Original research