Pathological features of the structure of the female genital organs from fetuses of mothers with complicated pregnancies
DOI:
https://doi.org/10.14739/2310-1210.2015.4.50301Keywords:
Fetus, Ovary, Pregnancy Complications, Pre-EclampsiyaAbstract
Aim. In the course of the study the structural features of fetal ovarian of mothers with severe preeclampsia in comparison with fetuses from healthy mothers were revealed.
Methods and results. Proliferation of connective tissue; mass mortality of the ovocytes; the prevalence of perishing primordial follicles in the follicular unit were demonstrated histologically. Histochemical methods established reduction in the intensity of the reaction to DNP in the nucleus and in the RNP in the cells cytoplasm. Morphometric method showed significant reduction in the relative volume of the follicular tissue, as well as a significant increase in the relative volume of the interstitial tissue. The described type of fetal ovarian structure of mothers with severe PE corresponds to hypoplastic type and constitutes a violation of the gonads formation in utero.
Conclusion. The revealed features of the fetal ovaries structure can contribute to a violation of the germinal function in the further ontogenesisReferences
Bashmakova, N. V., Kravchenko, E. N., & Lopushanskij, V. G. (2008). Rol' prognozirovaniya intranatal'nykh faktorov riska [Role predicting intrapartum risk factors]. Akusherstvo i ginekologiya, 3, 57– 61. [in Russian].
Boreichuk O. (2010) Kliniko-morfolohichnyi stan novonarodzhenykh vid materiv z vahitnistiu, uskladnenoiu hestozom [Zbigniew materіalіv XIV Mіzhnarodnogo medichnogo Congress studentіv that young vchenih]. Proceedings of the 14th Medical Congress, (рp. 147).Ternopil. [in Ukrainian].
Vaskov′skaya I. V., & Slepichko Yu. N. (2007) Sindrom zaderzhki vnutriutrobnogo razvitiya ploda pri gestozakh vtoroj poloviny beremennosti [Syndrome intrauterine growth retardation in the second half of pregnancy gestosis]. Novyny i perspektyvy medychnoi nauky; Proceedings of the 2nd International Conference, (рp. 5–6). Dnipropetrovsk. [in Ukrainian].
Subbotin, M. Ya., Laguchev, S. S., Oganesyan, T. G., et al. (1954). Gistologicheskaya tekhnika [Histology Equipment]. V.G. Eliseeva (Ed.). Moscow: Medgiz. [in Russian].
Markovskij, V. D., Sorokina, I. V., Gol'eva, N. V., & Kupriyanova, L. S. (2010) Rukovodstvo po gistologicheskoj, gistokhimicheskoj i immunogistokhimicheskoj tekhnike [Manual histological, histochemical and immunohistochemical techniques]. Kharkov: AdvAtm. [in Ukrainian].
Atramentova, L. A., & Utevskaya, О. М. (2008) Statisticheskie metody v biologii [Statistical Methods in Biology]. Gorlovka. [in Ukrainian].
Montgomery, S. C., Kinmond, S., Sardar, С., Siddique, J., Cooper, A., McGowan, S., et al. (2015). Short Stature Screening by Accurate Length Measurement in Infants with a Birth Weight <9th Centile. Horm. Res. Paediatr, 31, 51–54.
Dieber-Rotheneder, M., Beganovic, S., Lang, U., & Cervar-Zivkovic, M. (2012). Complex expression changes of the placental endothelin system in early and late onset preeclampsia, fetal growth restriction and gestational diabetes. Life Sci., 15(91), 710–5. doi: 10.1016/j.lfs.2012.04.040.
Lamarca, B. (2010). The role of immune activation in contributing to vascular dysfunction and the pathophysiology of hypertension during preeclampsia. Minerva Ginecol., 62, 105–20.
Moon, M., Baek, М., Ahn, Е., & Odibo, А. О. (2015). Association between small for gestational age and intrauterine fetal death: comparing a customized South Korean growth standard versus a population-based fetal growth chart. Matern. Fetal. Neonatal. Med., 8, 1–3. doi: 10.3109/14767058.2015.1027189.
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