Assessment of bone and mineral metabolism in women with deficiency of body weight at the planning stage of pregnancy
DOI:
https://doi.org/10.14739/2310-1210.2015.6.56308Keywords:
Body Mass Index, Bone Density, DensitometryAbstract
Body weight is one of the important parameters of somatic and reproductive health of women. Deficiency of body mass characterized by metabolic disorders and lead to various disorders of homeostasis.
Aim. Assessment of bone and mineral metabolism in 65 women with deficiency of body weight and 35 healthy women with normal weight who applied to the antenatal clinic for pregnancy planning.
Methods and results. Total calcium was determined in serum with colorimetric method, inorganic phosphorus — spectrophotometric method, parathyroid hormone, osteocalcin and vitamin D total (25(OH)D) — immunochemical method with electrochemiluminescent detection. Structural and functional state of bone were studied with ultrasound densitometry. It was determined that women with deficiency of body weight had changes in the calcium-regulating system, manifested statistically significant reduction in total calcium and calcium-regulating hormones, osteopenic syndrome observed in 32.3% (95% CI 22.2–44.4 %) cases.
Conclusion. Significant changes of bone and mineral metabolism occur in women with a body mass deficiency.
References
Gerasimova, L. I., Denisova, T. G., Gruzinova, E. N., & Vasilyeva, E. N. (2012) Deficit massy tela kak faktor riska reproduktivnykh poter' [Weight Deficit as a Risk Factor of Reproductive Losses]. Obshchestvennoe zdorov’e i zdravookhranenie, 2, 18–21 [in Russian].
Gruzinova, E. N., Gerasimova, L. I., Denisova, T. G., & Vasilyeva, E. N. (2012) Klinicheskaya ocenka reproduktivnoj funkcii zhenshchin s deficitom massy tela [Сlinical Assessment of the Reproductive Function of the Women with underweight]. Prakticheskaya medicina, 1, 23–25 [in Russian].
Bialo, S. R., & Gordon, C. M. (2014) Underweight, overweight, and pediatric bone fragility: impact and management. Curr. Osteoporos. Rep., 12(3), 319–328. doi: 10.1007/s11914-014-0226-z.
Chang, M. Y., Kuo, C. IL, & Chiang, K. F. (2010) The effects of pre-pregnancy body mass index and gestational weight gain on neonatal birth weight in Taiwan. International Journal of Nursing and Midwifery, 2(2), 28–34.
Pieńkowski, W., Wolski, H., Drews, K., & Seremak-Mrozikiewicz, A. (2015) Fetal programming and the etiology of osteoporosis. Ginekol Pol., 86(8), 622–625. doi: 10.17772/gp/58795.
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