Essential hypertensive controlled and normotensive patients. If there are differences?

Authors

  • V. V. Syvolap Zapozizhzhia State Medical University,
  • S. P. Zhemanyuk Zapozizhzhia State Medical University,

DOI:

https://doi.org/10.14739/2310-1210.2016.5.82543

Keywords:

Essential Hypertension, Blood Pressure, Ambulatory Blood Pressure Monitoring, Ambulatory Arterial Stiffness Index

Abstract

Ambulatory blood pressure monitoring (ABPM) is a modern method of blood pressure (BP) investigation recommended by international scientific associations for diagnostics of essential hypertension (EH). However, there are some methodological aspects which are not regulated. Particularly, ABPM parameters have not yet established for those patients in different age groups and pathologies.

The aim of the study was to determine peculiarities of ABPM parameters in treated controlled hypertensive and normotensive patients.

Materials and methods. 71 patients were included into the study and divided into two groups according to the level of 24-h systolic BP (SBP) and 24-h diastolic BP (DBP). There were 50 controlled patients with EH in the first group and 21 normotensive individuals without EH in the second group.

Results. In EH patients and normotensive individuals we had statistician difference of such parameters, like the hypertension time index (TI) of day SBP parameters (20 (8–31) % vs. 8 (4–18) %; р=0.040); of the square index (SI) of hypertension (24 (11–41) mm2/h vs. 8 (2–23) mm2/h; р=0.021); of the square index normalized (SIN) of hypertension (1.4 (0.6–2.4) U vs. 0.4 (0.1–1.2) U; р=0.018,) and the morning surge of SBP (45±14 mm Hg vs. 37±14 mm Hg; р=0.028, respectively). There is no different in other ABPM parameters.

Conclusion. The present data shows that treated controlled hypertensive patients and individuals without EH have statistician difference only in daily SBP of hypertensive indexes (TI, SI, SIN) and the morning surge of SBP. The other ABPM parameters, included new one, such as the arterial stiffness index, did not represent statistical difference between groups.

References

Kovalenko, V. M., & Kornatskyi V.M. (Eds) (2016) Problemy zdoroviia i medychnoii dopomogy ta model pokrashchennia v suchasnykh umovakh [Health and medical care problems, and up-to-day improvement model]. Kyiv: Gordon [in Ukrainian].

Pshenicyn, A. I., & Mazur, N. A. (2015) Sutochnoe monitorirovanie arterialnogo davlenia [Ambulatory blood pressure monitoring]. Moscow: Medpraktika-M. [in Russian].

Kovalenko, V. M. (Eds) (2016) Sertsevo-sudynni zakhvoriuvannia. Klasyifikatsiia, standarty diahnostyky ta likuvannia [Cardiovascular diseases: Classification, practical protocols of diagnosis and treatment]. Kyiv: Morion [in Ukrainian].

Dzyak, G. V., Kolesnik, T. V., & Pogoreckij, Yu. N. (2005) Sutochnoe monitorirovanie arterial´nogo davlenia [Ambulatory blood pressure monitoring]. Dnepropetrovsk [in Ukrainian].

Wendelin-Saarenhovi, M. L., Isoaho, R. E., Hartiala, J. J., Helenius, H. Y., Kivelä, S. L., Löppönen, M. K., & Hietanen, E. K. (2002) Ambulatory blood pressure characteristics in normotensive and threated hypertensive older people. J. of Human Hypertension, 16, 177–184.

O’Briend, E., Parati, G., Stergiouc, G., Asmar, R., Beilin, L., Bilo, G., et al. (2013) European society of hypertension position paper on ambulatory blood pressure monitoring J. Hypertens, 9, 1731–1768. doi: 10.1097/HJH.0b013e328363e964.

Parati, G., Stergiouc, G., O’Briend, Е., Asmar, R., Beilin, L., Bilo, G., et al. (2014) European society of hypertension practice guidelines for ambulatory blood pressure monitoring. J. Hypertens, 7, 1359–1369. doi: 10.1097/HJH.0000000000000221.

Boggia, J., Li, Y., Thijs, L., Hansen, T. W., Kikuya, M., Björklund-Bodegård, K., et al. (2007) International database on ambulatory blood pressure monitoring in relation to cardiovascular outcomes (IDACO) investigators. Prognostic accuracy of day versus night ambulatory blood: cohort study. Lancet, 370, 1219–1229.

Kario, K. (2010) Morning surge in blood pressure and cardiovascular risk evidence and perspectives Hypertension, 56, 765–773. doi: 10.1161/HYPERTENSIONAHA.110.157149.

Schillaci, G., Pussi, G. (2011) The relationship between systolic and diastolic blood pressure: a clinically meaningful slope? Hypertension Research, 34, 1175–1178. doi: 10.1038/hr.2011.161.

Mancia, G., Fagard, R., Narkiewicz, K., Redón, J., Zanchetti, A., Böhm, M., et al. (2013) The Task Force for the management of arterial hypertension of the European Hypertension Society (ESH) and of the European Society of Cardiology (ESC) 2013 ESH / ESC Guidelines for the management of arterial hypertension. J. Hypertens, 31, 1281–1357. doi: 10.1097/01.hjh.0000431740.32696.cc.

White, W. (2001) Blood pressure monitoring in cardiovascular medicine and therapeutics. New Jersey: Humana Press.

How to Cite

1.
Syvolap VV, Zhemanyuk SP. Essential hypertensive controlled and normotensive patients. If there are differences?. Zaporozhye medical journal [Internet]. 2016Nov.10 [cited 2024Apr.18];18(5). Available from: http://zmj.zsmu.edu.ua/article/view/82543

Issue

Section

Original research